National Sleep Foundation

Chapter 2: Insomnia


The decision to treat, the treatment choice, and when to end treatment are based on risk/benefit ratios (including the risk of not treating). In addition to the U.S. Food and Drug Administration (FDA)-approved drugs, many medications are used “off-label” to treat insomnia.

The following sections describe:

  • Hypnotics
  • Sedating Antidepressants
  • Other Agents to Treat Insomnia
  • Over-the-Counter Medications