National Sleep Foundation

Chapter 4: Primary Hypersomnias

Consequences

Behaviorally-induced ISS can lead to poor work performance, social withdrawal, depression, and other psychological problems.6 In one study, 22 of individuals diagnosed with Behaviorally-induced ISS reported having had accidents or near-miss accidents in the last five years.7 Behaviorally-induced ISS also causes long-term metabolic and endocrine dysfunction (e.g., decreased glucose tolerance)8, 9 and an impaired ability to mount a competent immune response.10

References

  1. Van Dongen HP, Maislin G, Mullington JM, Dinges DF. The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep. 2003;26:117-126.
  2. Komada Y, Inoue Y, Hayashida K, Nakajima T, Honda M, Takahashi K., “Clinical significance and correlates of behaviorally induced insufficient sleep syndrome,” Sleep Med. 2008 Dec;9(8):851-6. Epub 2007 Nov 5.
  3. Rosenthal L, Meixner R. Sleep Deprivation. In: Lee-Chiong TL, Sateia MJ, Carskadon MA, eds. Sleep Medicine. Philadelphia, Pa: Hanley and Belfus; 2002:85-92.
  4. Spiegel K, Laproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet. 1999;354:1435-1439.
  5. Spiegel K, Laproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet. 1999;354:1435-1439.