National Sleep Foundation

Chapter 7: Sleep-Related Movement Disorders

Treatment of Sleep-Related Bruxism (SB)

There is no cure for Sleep-Related Bruxism (SB). Dental guards or oral splints are the first line of treatment for SB, in order to prevent damage to teeth and other orofacial structures, relieve temporomandibular joint (TMJ) pain, and eliminate noises that disturb bed partners and/or family members.80

Pharmacological therapy has been met with limited success, although studies suggest that the anti-seizure medication clonazepam is effective at improving patients’ sleep efficiency, maintenance, latency, awakenings, and nocturnal wake time.81 82

References 

80 Dube C, Rompre PH, Manzini C, Guitard F, de Grandmont P, Lavigne GJ. Quantitative polygraphic controlled study on efficacy and safety of oral splint devices in tooth-grinding subjects. J Dent Res. 2004;83:398-403.
81 Saletu A, Parapatics S, Anderer P, Matejka M, Saletu B, “Controlled clinical, polysomnographic and psychometric studies on differences between sleep bruxers and controls and acute effects of clonazepam as compared with placebo,” Eur Arch Psychiatry Clin Neurosci. 2010 Mar;260(2):163-74. doi: 10.1007/s00406-009-0034-0. Epub 2009 Jul 15.
82 Huynh N, Manzini C, Rompré PH, Lavigne GJ, “Weighing the potential effectiveness of various treatments for sleep bruxism,” J Can Dent Assoc. 2007 Oct;73(8):727-30.