National Sleep Foundation

Chapter 7: Sleep Related Movement Disorders


How are sleep related leg cramps treated?

No systematic study has been published to date regarding treatment of sleep related leg cramps. Application of heat, movement of the affected limb, or stretching or massaging the muscle can provide relief. If severe, patients have variously reported benefits of quinine, magnesium, Vitamin E, and gabapentin.1


  1. Kannan N, Sawaya R. Nocturnal leg cramps: Clinically mysterious and painful-but manageable. Geriatrics. 2001;56:34-42.